Prolymphocyte
- Size : Medium, 12-15 ?m
- N/C ratio= Elevated, 0.9
- Cytoplasm
- Extension : Thin
- Basophilia : Intense
- Number of granules : Absent
- Color of granules : N/A
- Membrane : Regular
- Nucleus
- Situation : Central
- Chromatin : Dense
- Nucleoli : Present
- Membrane : Regular
- Normal values : Absent in the blood and in bone marrow
- Description / Pathology :
Medium size cell larger than a lymphocyte, round nucleus with dense chromatin presenting prominent nucleolus, poorly extended light basophilic cytoplasm.
Often in a context of major lymphocytosis.
Prolymphocytic Leukemia: transformation of CLL into prolymphocytic leukemia